Nitro 505 EC (Chlorpyrifos + Cypermethrin) – 100 ml – Auto Crop Care Ltd

Description

Nitro 505 EC (Chlorpyrifos + Cypermethrin)

 

Nitro 505 EC is a strong, broad-spectrum chemical insecticide—not a general-purpose garden pesticide—and its Bangladesh-approved uses are narrower than the list of pests that the two active ingredients can theoretically kill.

Nitro 505 EC — Quick profile

Property	Information
Product	Nitro 505 EC
Registration	AP-1138 in Bangladesh
Manufacturer/registrant listed by DAE	Auto Crop Care Limited
Formulation	EC — Emulsifiable Concentrate
Active ingredients	Chlorpyrifos 50% + Cypermethrin 5%
Active ingredient concentration	500 g/L chlorpyrifos + 50 g/L cypermethrin
Chemical classes	Organophosphate + synthetic pyrethroid
Action	Contact + stomach; formulation sources also describe vapour/fumigant action
General character	Broad-spectrum insecticide
Bangladesh registered crops for Nitro 505 EC	Potato, cotton, sugar beet, tea
Major registered pests	Aphid, jassid, whitefly, caterpillar/Spodoptera, termite

The Bangladesh Department of Agricultural Extension’s registered-pesticide list identifies Nitro 505 EC specifically as Chlorpyrifos 50% + Cypermethrin 5%, AP-1138, with uses on potato, cotton and tea; a Bangladesh product source additionally gives sugar beet/Spodoptera. (Department of Agricultural Extension)

Benefits in gardening and agriculture

Nitro 505 EC has several useful characteristics:

1. Broad-spectrum pest control

Because it combines two insecticides with different modes of action, it can affect a relatively broad range of insect pests.

Chlorpyrifos is an organophosphate insecticide, while cypermethrin is a synthetic pyrethroid. (PubChem)

This combination can provide control against:

• Aphids
• Jassids/leafhoppers
• Whiteflies
• Thrips
• Caterpillars
• Cutworm-type larvae
• Bollworms
• Stem borers
• Leaf folders
• Fruit/shoot borers
• Spodoptera
• Termites
• Some other chewing and sucking insects

However: these are capabilities reported for this active-ingredient combination across different products/labels. They should not automatically be interpreted as approved uses for Nitro 505 EC in Bangladesh.

1. Contact action

The insect can be killed when the spray comes into direct contact with its body.

1. Stomach action

Insects can be poisoned after feeding on treated plant material.

1. Fast knock-down

The cypermethrin component can provide relatively rapid neurotoxic action, producing characteristic knock-down/paralysis.

1. Two different modes of action

This is one of the principal advantages of the combination.

• Chlorpyrifos → acetylcholinesterase inhibition
• Cypermethrin → disruption of voltage-gated sodium channels

That means the insect is attacked through two fundamentally different neurological pathways. (PubChem)

1. Useful against both sucking and chewing insects

This makes the formulation potentially useful where a crop has mixed infestations.

1. Some soil/hidden-pest activity

Chlorpyrifos has historically been used against soil-dwelling pests and termites, although soil application should only be made where the specific product label/registration permits it.

General application rate

There is no single universal rate for Nitro 505 EC.

The Bangladesh information I found gives the following registered rates:

Crop	Target pest	Nitro 505 EC rate
Potato	Aphid	1 ml/L water
Cotton	Aphid, jassid, whitefly	600 ml/ha
Sugar beet	Caterpillar / Spodoptera litura	4.5 L/ha
Tea	Termite	4 L/ha

These figures come from Bangladesh registration/product information. (Department of Agricultural Extension)

Important

Do not take the highest or lowest of these and use it as a universal garden dosage.

For example:

1 ml/L ≠ appropriate for every crop or pest.

The difference in rates is enormous because application method, crop canopy, pest biology, formulation exposure and required active-ingredient dose vary.

Best method/practice to use it

For a permitted foliar application, the general practice is:

Step 1 — Identify the pest

Do not spray merely because you see “something moving.”

Identify whether it is:

• Aphid
• Whitefly
• Jassid
• Caterpillar
• etc.

Step 2 — Confirm that Nitro 505 EC is registered for that crop/pest

This is especially important in Bangladesh.

Step 3 — Calculate the required amount

Follow the product label/registered rate, rather than estimating.

Step 4 — Prepare spray mixture

Use clean water and add the measured pesticide according to the label directions.

For an EC formulation, adequate agitation is important.

Step 5 — Spray thoroughly

For foliar pests, aim for good coverage of:

• upper leaf surfaces
• lower leaf surfaces
• stems
• pest-infested areas

But avoid excessive runoff.

Step 6 — Spray during appropriate weather

Prefer:

early morning or late afternoon/evening

Avoid:

• strong midday sunlight
• strong wind
• imminent rain
• extreme heat

Step 7 — Do not automatically repeat

Re-application should be based on the label, pest pressure and required interval.

Step 8 — Rotate insecticide modes of action

Repeatedly using the same chemistry can accelerate insecticide resistance.

Precautions required during application

This is one of the most important sections.

Nitro 505 EC should be treated as a hazardous agricultural pesticide, not as an ordinary gardening product.

Personal protection

Wear:

• Chemical-resistant gloves
• Long-sleeved clothing
• Long trousers
• Closed shoes/boots
• Eye protection
• Appropriate respiratory protection where the label/SDS requires it

Never:

• Eat while spraying
• Drink while spraying
• Smoke while spraying
• Touch your face with contaminated gloves
• Spray against the wind
• Spray near children
• Allow children to handle the product
• Pour pesticide into food/drink containers

Keep away from:

• Children
• Pets
• Food
• Animal feed
• Drinking water
• Fish ponds
• Aquariums
• Beehives

Bees are particularly important

Chlorpyrifos is highly toxic to adult honeybees under acute exposure, according to EPA risk-assessment information. (EPA NEPIS)

Therefore:

Do not spray flowering plants when bees are actively foraging.

Fish/aquatic organisms

Cypermethrin is particularly concerning for aquatic organisms/fish; PubChem notes that pyrethroids can be toxic to fish even though they generally break down relatively rapidly in sunlight/atmosphere. (PubChem)

Therefore:

Never allow spray, concentrate or contaminated runoff to enter ponds, drains or waterways.

After spraying

Wash:

• Hands
• Face
• Exposed skin

Wash contaminated clothing separately.

Clean equipment appropriately.

Suitable crops and corresponding application rates

For Nitro 505 EC specifically in Bangladesh, the clearest registered information I found is:

Crop	Pest	Application rate
🥔 Potato	Aphid	1 ml/L water
🌱 Cotton	Aphid, Jassid, Whitefly	600 ml/ha
🌱 Sugar beet	Caterpillar / Spodoptera litura	4.5 L/ha
🍃 Tea	Termite	4 L/ha

The Bangladesh DAE registration list confirms the Nitro 505 EC/AP-1138 entries, including potato, cotton and tea. (Department of Agricultural Extension)

Other crops reported for the same active-ingredient formulation

Other commercial products containing Chlorpyrifos 50% + Cypermethrin 5% EC have labels/recommendations for crops such as:

• Rice/paddy
• Cotton
• Okra
• Cabbage
• Vegetables

with pests such as:

• Stem borer
• Leaf folder
• Bollworm
• Jassid
• Thrips
• DBM
• Fruit/shoot borers

For example, other formulation labels report rice and cotton uses. (Global Crop Care)

But do not transfer those rates to Nitro 505 EC unless the Nitro label/DAE registration specifically permits that use.

Effectiveness

There is no scientifically valid single percentage effectiveness for Nitro 505 EC.

For example, “95% effective” could be true against one susceptible pest under one field condition but completely wrong for another pest or resistant population.

So I would rate it qualitatively:

Aspect	Estimated rating
Broad-spectrum insect control	9/10
Sucking insects	8.5/10
Caterpillars	8.5/10
Termites	8/10
Fast knock-down	9/10
Overall insecticidal strength	8.5/10
Universal garden usefulness	6/10

If you insist on a percentage

A reasonable non-scientific comparative estimate would be:

~80–90% potential control effectiveness against susceptible, correctly targeted pests under appropriate application conditions.

I would not label that as a guaranteed “90% kill rate.”

Actual control depends on:

• pest species
• life stage
• resistance
• concentration
• spray coverage
• weather
• crop
• infestation severity
• timing

Toxicity

This needs an important correction.

Toxicity cannot meaningfully be expressed as “75% toxic.”

Toxicity is normally described using measurements such as:

• LD50
• LC50
• NOAEL
• exposure concentration
• hazard classification

So a “toxicity percentage” would be scientifically misleading.

Practical hazard rating

For human/environmental pesticide handling, I would characterize Nitro 505 EC as:

High hazard — approximately 8/10 as a practical handling-risk rating.

This is not an official toxicity score.

Why?

Chlorpyrifos

Chlorpyrifos is an organophosphate cholinesterase inhibitor. Its toxicological mechanism involves conversion to chlorpyrifos-oxon and inhibition of acetylcholinesterase. (PubChem)

Cypermethrin

Cypermethrin is a synthetic pyrethroid neurotoxin acting primarily on voltage-sensitive sodium channels. (PubChem)

Environmental concern

Particularly important:

• Bees
• Fish/aquatic organisms
• Beneficial insects
• Other non-target organisms

Therefore I would classify it as:

Human handling hazard: 8/10
Bee/non-target insect hazard: 9/10
Aquatic hazard: 9/10

These are comparative practical ratings, not regulatory toxicity scores.

Target pests

For Nitro 505 EC’s Bangladesh-registered uses, the confirmed targets include:

• Aphids
• Jassids
• Whiteflies
• Caterpillars
• Spodoptera litura
• Termites

The exact Bangladesh registration specifically lists potato aphid, cotton aphid/jassid/whitefly, sugar-beet caterpillar/Spodoptera and tea termite. (Department of Agricultural Extension)

Across other products using the same 50% + 5% formulation, additional reported targets include:

• Thrips
• Bollworms
• Pink bollworm
• American bollworm
• Leaf folder
• Stem borer
• Fruit borer
• Shoot borer
• DBM
• Cutworm
• Other chewing caterpillars

These should be treated as formulation-level capabilities, not automatically Nitro 505 EC’s Bangladesh-approved claims. (Bharat Certis AgriScience)

Chemical formula

There isn’t one molecular formula for Nitro 505 EC because it is a formulated mixture.

Chlorpyrifos

C₉H₁₁Cl₃NO₃PS

Molecular weight ≈ 350.6 g/mol. (PubChem)

Cypermethrin

C₂₂H₁₉Cl₂NO₃

Molecular weight ≈ 416.3 g/mol. (PubChem)

Chemical contents

For the Nitro 505 EC formulation:

Active ingredients

Chlorpyrifos — 50% w/w

Cypermethrin — 5% w/w

Therefore:

Total active ingredient = 55% w/w

The remaining approximately 45% consists of formulation ingredients such as solvents, emulsifiers, stabilizers and other inert/formulation components. The exact identities and percentages are manufacturer-specific and should be obtained from the product’s SDS/formulation specification.

The Bangladesh source identifies the formulation as 50% chlorpyrifos + 5% cypermethrin, while technical labels for the same formulation confirm the composition. (Department of Agricultural Extension)

Shelf life

I could not verify an authoritative Nitro 505 EC-specific shelf-life figure from the sources available to me.

Therefore, I would not confidently state “2 years” or “3 years” as the official Nitro shelf life without seeing the actual label/bottle.

Practical recommendation

Check the original bottle for:

• Manufacturing date
• Expiry date
• Batch number
• Registration number

Do not use an expired product simply because the liquid still looks normal.

Storage should generally be:

cool + dry + well ventilated + locked + away from sunlight + away from food/feed + inaccessible to children.

How it is made/produced

At a high level, Nitro 505 EC is a formulated pesticide, not a single chemical synthesized in one step.

Stage 1 — Active ingredient production

The two active ingredients are manufactured separately through industrial chemical synthesis:

Chlorpyrifos

An organophosphorus pesticide synthesized from chemical intermediates involving chlorinated pyridinol and phosphorus-containing chemistry.

Cypermethrin

A synthetic pyrethroid produced through esterification/chemical synthesis involving substituted cyclopropane-carboxylic-acid and phenoxybenzyl-type components.

Stage 2 — Formulation

The purified technical active ingredients are combined with:

• Organic solvent/carrier
• Emulsifiers
• Stabilizers
• Other formulation additives

to produce an EC (Emulsifiable Concentrate).

Stage 3 — Quality control

The finished formulation is tested for parameters such as:

• Active ingredient concentration
• Physical stability
• Emulsion characteristics
• Storage stability
• Packaging compatibility

Stage 4 — Packaging

The concentrate is packaged into pesticide-compatible containers.

It is then sold as a concentrated liquid that is diluted with water before permitted agricultural application.

Other uses apart from gardening

Historically, chlorpyrifos has had uses beyond crop gardening.

Chlorpyrifos

Reported uses have included:

• Agricultural pest control
• Termite control
• Structural pest control
• Cockroach control
• Flea control
• Tick control
• Livestock-related pest control

PubChem/ATSDR information notes historical household uses for cockroaches, fleas and termites and agricultural use against crop pests and cattle ticks. (PubChem)

Cypermethrin

Cypermethrin is used principally as an insecticide and has applications in pest-control contexts beyond agriculture.

However:

Nitro 505 EC itself should not be repurposed for household, livestock or structural pest control unless its label specifically authorizes that use.

Biology behind elimination of pests

This is where Nitro 505 EC becomes particularly interesting.

It effectively attacks the insect nervous system through two different biological pathways.

Chlorpyrifos pathway

Normally:

Neuron → acetylcholine → nerve signal → acetylcholinesterase removes acetylcholine → signal stops

Chlorpyrifos is metabolized into its more active oxon form.

Then:

Chlorpyrifos → chlorpyrifos-oxon → inhibits acetylcholinesterase

Consequently:

Acetylcholine accumulates → continuous nerve stimulation → uncontrolled muscle activity → paralysis → death

This is the fundamental biological basis of organophosphate insecticidal action. (PubChem)

Chemistry behind elimination of pests

1. Chlorpyrifos

Chemically, chlorpyrifos is an organophosphorothioate.

Its molecular formula is:

C₉H₁₁Cl₃NO₃PS

Its toxicologically important transformation is approximately:

Chlorpyrifos → Chlorpyrifos-oxon

The oxon is a potent acetylcholinesterase inhibitor.

It interacts with the active site of AChE, preventing the enzyme from efficiently breaking down acetylcholine. (PubChem)

1. Cypermethrin

Cypermethrin is a synthetic pyrethroid:

C₂₂H₁₉Cl₂NO₃

Its main target is the voltage-gated sodium channel of nerve cells.

Normally:

Sodium channel opens → Na⁺ enters → nerve impulse → channel closes

Cypermethrin interferes with normal channel closure.

Therefore:

Prolonged Na⁺ influx → prolonged depolarization → repetitive nerve firing → nervous-system disruption → paralysis → death.

PubChem describes pyrethroid action primarily through effects on voltage-sensitive sodium channels and prolonged channel opening. (PubChem)

Why the combination can be powerful

This is the major chemistry/biology advantage:

Chlorpyrifos

AChE inhibition

↓

Excess acetylcholine

↓

Continuous nerve stimulation

↓

Paralysis

Cypermethrin

Sodium-channel disruption

↓

Abnormal Na⁺ movement

↓

Nerve hyperexcitation

↓

Paralysis

So the insect is subjected to two different neurotoxic mechanisms simultaneously.

That helps explain why Chlorpyrifos 50% + Cypermethrin 5% products are marketed as broad-spectrum insecticides with quick knock-down. (Bharat Certis AgriScience)

⚠ Very important information for home gardening

If your purpose is to decide whether Nitro 505 EC should be recommended to a residential gardener, I would not make it the first-choice general garden pesticide.

It is a powerful broad-spectrum insecticide, but the same characteristics that make it effective also make it problematic around:

• Children
• Pets
• Edible vegetables
• Herbs
• Fruit
• Flowering plants
• Bees
• Beneficial insects
• Fish ponds
• Rooftop gardens

And there is another important issue:

“The chemical can kill a pest” does not mean “the product is legally registered for that pest/crop.”

For example, a 50% chlorpyrifos + 5% cypermethrin product may have a label for rice stem borer in one country/product while Nitro 505 EC’s Bangladesh registration may not authorize that use.

The Bangladesh DAE registration is therefore the safer basis for recommending Nitro 505 EC in Bangladesh. (Department of Agricultural Extension)

Info Sources

1. Bangladesh Department of Agricultural Extension — Registered Agricultural Pesticides List — Nitro 505 EC/AP-1138 and Bangladesh crop/pest registrations. (Department of Agricultural Extension)

   Bangladesh DAE registered pesticide list

2. Plantium Bangladesh — Nitro 505 EC — formulation, active ingredient concentration and Bangladesh application rates. (Fancy Planting Bangladesh)

   Plantium — Nitro 505 EC

3. PubChem — Chlorpyrifos — molecular formula and mechanism. (PubChem)

   PubChem — Chlorpyrifos

4. PubChem — Cypermethrin — molecular formula, chemistry and mechanism. (PubChem)

   PubChem — Cypermethrin

5. EPA — Chlorpyrifos risk assessment — environmental/honeybee toxicity information. (EPA NEPIS)
6. FMC Nurocombi label — technical formulation information for Chlorpyrifos 50% + Cypermethrin 5% EC. (FMC Ag US)
7. Bharat Certis — Bilbo B-505 — formulation characteristics and example crop/pest claims for the same active-ingredient combination. (Bharat Certis AgriScience)
8. Global Crop Care — Impact 505 — formulation and example crop/pest recommendations. (Global Crop Care)
9. NaPanta — Chlorpyrifos 50% + Cypermethrin 5% EC — additional formulation-level crop/pest information. (NaPanta®)

Bottom line

Nitro 505 EC = Chlorpyrifos 50% + Cypermethrin 5% EC, and I would rate its pest-killing power around 8.5/10, but its general residential-gardening suitability only around 6/10 because it is a broad-spectrum, relatively hazardous pesticide.

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